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Dermatan Sulphate Proteoglycans - Chemistry, Biology, Chemical Pathology

New ISBN 9781855780514
Old ISBN 1855780518
Format: Hardback
Pages: 384
Price: GBP 75.00
Members Price: GBP 56.25
Date Published: November 1993
Published by: Portland Press Ltd

Edited by JE Scott

University of Manchester, UK

General

This book brings new perspectives to extracellular matrix studies, embodying an approach to proteoglycans and glycosa-minoglycans in which their function is directly linked to their chemical morphology.

Dermatan sulphate proteoglycans (PDSs) are bifunctional cross-linking molecules, acting as tissue organizers. Molecular recognition between dermatan sulphate chains is discussed, as part of a chemical overview of the primary, secondary and tertiary structures of dermatan sulphate and its protein carriers.

Contents:

  • Part I - Nomenclature of Dermatan / Chondroitin Glycans and their Proteoglycans
  • Part II - Chemistry of Glycan Chains
  • Part III - Structures of the Protein Cores
  • Part IV - Biosynthesis of Dermatan Sulphate Chains
  • Part V - Chemical Morphology of Dermatan Sulphate Proteoglycans
  • Part VI - Molecular Interactions Involving Dermatan Sulphate
  • Part VII - Pathobiochemistry of Dermatan Sulphate
  • Bibliography
  • Index

Reviews:
"I think this book is an excellent buy for anyone interested in proteoglycans and their complex physical and biological properties."
Trends in Cell Biology

"this book will be indispensable for every worker in the field and should certainly be recommended for the library as an essential reference text."
Journal of Anatomy

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