Books

Essays in Biochemistry Volume 35
Molecular Motors

Available Online

Edited by SJ Higgins and G Banting

University of Leeds and University of Bristol, UK

Essays in Biochemistry

Molecular motors are the molecules (or assemblies of molecules) which drive a range of processes (e.g. organellar movement, chromosome segregation, movement of restriction enzymes, flagellar movement) in cells. Thus, they play pivotal roles in diverse cellular function. Several human disorders involve defects in molecular motor systems. Understanding their structures, mechanisms of action and varied roles is therefore of great practical importance. This volume aims to provide up-to-date information about molecular motors whilst at the same time conveying the excitement of the field. It consists of short, punchy review articles (written by internationally respected experts) which explain the latest advances, the applications of new technology, and point to the future. One of the principal aims of the volume is to inspire young scientists to want to work in this area.

"...the book on molecular motors makes for a terrific read while riding in a car, a train, an airplane, or just sitting at your desk."
James R. Sellers, Trends in Biochemical Sciences

Contents:

• Introduction R Cross
  
• F1-ATPase: a highly efficient rotary ATP machine K Kinosita et al.
  
• Motors in muscle: the function of conventional myosin II CR Bagshaw
  
• Unconventional myosins G Kalhammer and M Bähler
  
• Muscle, myosin and single molecules AE Knight and JE Molloy
  
• Motor proteins of the kinesin superfamily: structure and mechanism FJ Kull
  
• The molecular anatomy of dynein A Harrison and SM King
  
• Microtubule-based transport along axons, dendrites and axonemes D Signor and JM Scholey
  
• The molecular motors of cilia and eukaryotic flagella D Woolley
  
• Translational elongation factor G: a GTP-driven motor of the ribosome
  W Wintermeyer and MV Rodnina
  
• How do proteins move along DNA? Lessons from type-I and type-III restriction endonucleases MD Szczelkun
  
• Molecular motors in the heart F Davison et al.
  
• The roles of unconventional myosins in hearing and deafness RT Libby and
  KP Steel
  
  

Sales enquiries Portland Customer Services Portland Press Ltd. Commerce Way Colchester CO2 8HP UK Tel: +44 (0)1206 796351 Fax: +44 (0)1206 799331 E-mail: sales@portland-services.com Map

Editorial enquiries Portland Press Ltd. Third floor Charles Darwin House 12 Roger Street London WC1N 2JU Tel: +44(0) 20 7685 2410 Fax: +44(0) 20 7685 2469 E-mail: editorial@portlandpress.com