Books

Essays in Biochemistry Volume 34
Metalloproteins

Available Online

Edited by D Ballou

University of Michigan, USA

Essays in Biochemistry

Metals are involved in most segments of the chemistry of life, including respiration, numerous steps of metabolism, photosynthesis, nitrogen fixation, nerve transmission, signal transduction, muscle contraction, oxygen transport and protection from xenobiotic compounds. In addition, metals are used in medicine as therapeutic agents. This volume attempts to show many of the roles of metals in a variety of circumstances that are used widely in biology.

The 12 chapters of this volume are written by several of the best-known experts in their specialities. They have tried to present their subjects with a view to teaching principles of chemistry and showing methods of how to develop an understanding of the functions of metals, outlining the roles of metals in a variety of biological functions and presenting perspectives on the future of research in bioinorganic chemistry.

Contents:

• The role of efflux in bacterial resistance to soft metals and metalloidsm
  BP Rosen
  
• Bacterial detoxification of Hg(II) and organomercurials SM Miller
  
• Non-haem iron-containing oxygenases involved in the microbial biodegradation of aromatic hydrocarbons ED Coulter and DP Ballou
  
• Haem iron-containing peroxidases IS Isaac and JH Dawson
  
• Nature's universal oxygenases: the cytochromes P450 SG Sligar
  
• Oxygen-carrying proteins: three solutions to a common problem' DM Kurtz, Jr.
  
• Biological electron-transfer reactions AG Mauk
  
• Molybdenum enzymes R Hille
  
• Coenzyme B12 (cobalamin)-dependent enzymes ENG Marsh
  
• Oxygen reactions of the copper oxidases JW Whittaker
  
• Catechol dioxygenases JB Broderick
  
• Cisplatin EE Trimmer and JM Essigmann
  
• Subject index
  

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