Books

Biochemical Society Symposia Volume 67
Neuronal Signal Transduction and Alzheimer s Disease

Available Online

Edited by C'O Neill and B Anderton

University College, Cork, Ireland and Institute of Psychiatry, London, UK

Biochemical Society Symposia

This volume in the Biochemical Society Symposium series brings together key researchers from diverse biochemical areas to focus upon signal transduction dysfunction in Alzheimer's disease. Although specifically focused upon Alzheimer's this book has many parallels in other neurodegenerative disorders and will be of interest to those studying neuronal cell development and function in health and disease.

Contents:

• Modulation of -amyloid production and fibrillization D Allsop et al.
• Alzheimer's disease: inside, outside, upside down SD Yan et al.
• The role of post-translational modification in -amyloid precursor protein processing N Georgopoulou et al.
• Alzheimer's disease: dysfunction of a signalling pathway mediated by the amyloid precursor protein? RL Neve et al.
• Genetic dissection of primary neurodegenerative diseases J Hardy
• tau gene mutations and neurodegeneration M Goedert and MG Spillantini
• Sites of phosphorylation in tau and factors affecting their regulation BH Anderton et al
• Neurofibrillary tangles and tau phosphorylation Jean-Pierre Brion et al
• Presenilin function: connections to Alzheimer's disease and signal transduction PE Fraser et al
• Apolipoprotein E and Alzheimer's disease: signal transduction mechanisms WJ Strittmatter
• The Apolipoprotein E gene and Alzheimer's disease - is tau the link?
  S Lovestone et al.
• Apolipoprotein E and A4-amyloid: signals and effects TG Ohm et al
• Regulation of gene expression by muscarinic acetylcholine receptors
  H von der Kammer et al.
• Oxidative signalling and inflammatory pathways in Alzheimer's disease
  I Anderson et al
• Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease MP Mattson et al.
• Receptor-G-protein signalling in AD RF Cowburn et al.
• Dysfunctional intracellular calcium homeostasis: a central cause of neurodegeneration in Alzheimer's disease C O' Neill et al.
• Transgenic mouse models of Alzheimer's disease: phenotype and mechanisms of pathogenesis K Duff
• Modelling Alzheimer's disease in multiple transgenic mice I Dewachter et al.

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