A critical review of current biological monitoring techniques for the assessment of exposure to low levels of benzene
New ISBN 9780852933008
Old ISBN 0852933002
Date Published: July 2000
Published by: Energy Institute
Although direct evidence of harm at low levels of exposure to benzene is absent, benzene is a genotoxic carcinogen and as such there is continuing concern over the effects of long-term continuous exposure in both occupational settings and the general environment. The toxicity of benzene in human populations, particularly those exposed at workplace is well established in studies, where levels are in excess of 10ppm. Air monitoring, however, even when carried out using personal air sampling, does not give an indication of the total dose of benzene absorbed by the human body, particularly at low levels of exposure.
Biological Monitoring and Biological Effect Monitoring, therefore, can be important supplements to air monitoring.Under the Advisory Committee on Health and with the guidance of the Department of Environmental and Occupational Medicine at the University of Newcastle upon Tyne, the Institute of Petroleum has developed this publication which provides a review of current biological monitoring techniques for the assessment of exposure to benzene and the routes of exposure, uptake, metabolism and excretion.